A primary care visit in a few drops of blood.

A single, self-administered blood sample, just 500 µL, captures the signals your body is sending today and maps where your health is going next.

DIGITAL HEALTH TWIN

DIGITAL HEALTH TWIN

DIGITAL HEALTH TWIN

A living model of your biology, contextualized for risk.

Manifold Health uses these signals to construct a Digital Health Twin: a continuously updated, computational model of your biology that connects molecular data to real-world health outcomes.

Digital twin pipeline

Gold standard blood data

No manual interpretation - Biological signals are automatically structured and normalized.

No manual interpretation - Biological signals are automatically structured and normalized.

No manual interpretation - Biological signals are automatically structured and normalized.

Early signal alerts can detect meaningful biological deviations and compounding risk patterns.

Early signal alerts can detect meaningful biological deviations and compounding risk patterns.

Early signal alerts can detect meaningful biological deviations and compounding risk patterns.

As new data arrives, the Digital Health Twin updates in real time—tracking how systems evolve rather than capturing static snapshots.

As new data arrives, the Digital Health Twin updates in real time—tracking how systems evolve rather than capturing static snapshots.

As new data arrives, the Digital Health Twin updates in real time—tracking how systems evolve rather than capturing static snapshots.

Incorporate individual history, demographics, and longitudinal context to refine predictions.

Incorporate individual history, demographics, and longitudinal context to refine predictions.

Incorporate individual history, demographics, and longitudinal context to refine predictions.

Clean, filtered exports you can share instantly.

Clean, filtered exports you can share instantly.

Clean, filtered exports you can share instantly.

Costs Compound

Costs Compound

Costs Compound

Detect conditions early for better outcomes

Every lifestyle-related chronic condition managed earlier saves tens of thousands in treatment costs and delivers 2–3x better health outcomes on average.

Continuous biological monitoring

Track key biological systems over time as new blood data is collected. Manifold Health updates the Digital Health Twin continuously—revealing subtle changes long before clinical symptoms emerge.

Continuous biological monitoring

Track key biological systems over time as new blood data is collected. Manifold Health updates the Digital Health Twin continuously—revealing subtle changes long before clinical symptoms emerge.

Continuous biological monitoring

Track key biological systems over time as new blood data is collected. Manifold Health updates the Digital Health Twin continuously—revealing subtle changes long before clinical symptoms emerge.

System-level thresholds limits & rules

Define biologically meaningful ranges across metabolic, inflammatory, cardiovascular, and hormonal systems. Our models evaluate how signals interact—rather than relying on isolated biomarkers.

System-level thresholds limits & rules

Define biologically meaningful ranges across metabolic, inflammatory, cardiovascular, and hormonal systems. Our models evaluate how signals interact—rather than relying on isolated biomarkers.

System-level thresholds limits & rules

Define biologically meaningful ranges across metabolic, inflammatory, cardiovascular, and hormonal systems. Our models evaluate how signals interact—rather than relying on isolated biomarkers.

Early deviation detection

Identify when biology begins to drift from healthy trajectories. Manifold Health flags compounding risk patterns early—when intervention is still effective and outcomes are more favorable.

Early deviation detection

Identify when biology begins to drift from healthy trajectories. Manifold Health flags compounding risk patterns early—when intervention is still effective and outcomes are more favorable.

Early deviation detection

Identify when biology begins to drift from healthy trajectories. Manifold Health flags compounding risk patterns early—when intervention is still effective and outcomes are more favorable.

Report Engine

Report Engine

Report Engine

Turn bloodwork into into risk insight — instantly.

From screening, to rising risks, to escalations, Manifold Health generates polished reports that help you make decisions faster.

Generate report

Generate report

Generate report

Rising Risk Parameters

Rising Risk Parameters

Rising Risk Parameters

RR report - Q2

RR report - Q2

RR report - Q2

July 18, 2025

July 18, 2025

July 18, 2025

Escalations

Escalations

Escalations

EE report - Apr 2025

EE report - Apr 2025

EE report - Apr 2025

June 1, 2025

June 1, 2025

June 1, 2025

Your reports

Your reports

Your reports

One-click report builder

Select your filters, timeframes, and metrics — Manifold Health automatically compiles the data into consistent, shareable reports, formatted for clarity.

One-click report builder

Select your filters, timeframes, and metrics — Manifold Health automatically compiles the data into consistent, shareable reports, formatted for clarity.

One-click report builder

Select your filters, timeframes, and metrics — Manifold Health automatically compiles the data into consistent, shareable reports, formatted for clarity.

Automated insights

Manifold Health scans your risk activity for trends, shifts, or inconsistencies and turns them into clear takeaways without manual digging.

Automated insights

Manifold Health scans your risk activity for trends, shifts, or inconsistencies and turns them into clear takeaways without manual digging.

Automated insights

Manifold Health scans your risk activity for trends, shifts, or inconsistencies and turns them into clear takeaways without manual digging.

Multiple export formats

Download or share reports in the format that suits your audience — from polished PDFs to raw CSVs or real-time Google Sheets.

Multiple export formats

Download or share reports in the format that suits your audience — from polished PDFs to raw CSVs or real-time Google Sheets.

Multiple export formats

Download or share reports in the format that suits your audience — from polished PDFs to raw CSVs or real-time Google Sheets.

Woman holding a smartphone looking through the glass

Key Insights

Focused on the key conditions responsible for most preventable healthcare costs.

Woman holding a smartphone looking through the glass

Key Insights

Focused on the key conditions responsible for most preventable healthcare costs.

Woman holding a smartphone looking through the glass

Key Insights

Focused on the key conditions responsible for most preventable healthcare costs.

Why health systems are moving to Manifold Health

Traditional healthcare tools keep teams reactive.
Manifold Health enables earlier insight, clearer decisions, and better outcomes—before disease and cost escalate.

Legacy healthcare tools

Episodic, visit-based care built around symptoms

Fragmented data spread across labs, providers, and systems

Static reports that arrive too late to change outcomes

Isolated biomarkers interpreted without biological context

Reactive interventions triggered after disease progression

Limited ability to model risk or forecast trajectories

Surprise fees for integrations and support.

Poor reporting, limited to static exports.

Vectura

Built specifically for modern finance operations.

Clean, intuitive interface designed for speed.

One platform — expenses, budgets, vendors.

Smart approval flows with built-in controls.

Real-time insights with budget health indicators.

Up and running in days with guided implementation.

Transparent pricing with everything included.

Dynamic, customizable reports you can actually use.

Legacy healthcare tools

Episodic, visit-based care built around symptoms

Fragmented data spread across labs, providers, and systems

Static reports that arrive too late to change outcomes

Isolated biomarkers interpreted without biological context

Reactive interventions triggered after disease progression

Limited ability to model risk or forecast trajectories

Surprise fees for integrations and support.

Poor reporting, limited to static exports.

Vectura

Built specifically for modern finance operations.

Clean, intuitive interface designed for speed.

One platform — expenses, budgets, vendors.

Smart approval flows with built-in controls.

Real-time insights with budget health indicators.

Up and running in days with guided implementation.

Transparent pricing with everything included.

Dynamic, customizable reports you can actually use.

Legacy healthcare tools

Episodic, visit-based care built around symptoms

Fragmented data spread across labs, providers, and systems

Static reports that arrive too late to change outcomes

Isolated biomarkers interpreted without biological context

Reactive interventions triggered after disease progression

Limited ability to model risk or forecast trajectories

Surprise fees for integrations and support.

Poor reporting, limited to static exports.

Vectura

Built specifically for modern finance operations.

Clean, intuitive interface designed for speed.

One platform — expenses, budgets, vendors.

Smart approval flows with built-in controls.

Real-time insights with budget health indicators.

Up and running in days with guided implementation.

Transparent pricing with everything included.

Dynamic, customizable reports you can actually use.

The Manifold Health shift straight from our partners

Hear how Manifold Health is helping teams move from reactive care to earlier insight and better outcomes.

Clara Nguyen

Head of Finance

“Manifold Health gave us immediate visibility into biological risk across systems. We identified multiple early deviations in the first week—and now every decision is grounded in real-time biological data.”

37%

Reduction in budget overages

2x

Faster spend approvals

Darius Finch

Finance Director

“Before Manifold Health, we were reacting to fragmented data and late signals. Now we have a unified view of biology, continuously updated insight, and early alerts—meaning fewer surprises and more time to focus on long-term health outcomes.”

3.4 h

Saved per team member each week

45%

Fewer manual reconciliation tasks

Meera Shah

Controller

“Manifold Health dramatically improved the clarity and reliability of our biological data. Our insights are cleaner, our team is less reactive, and we finally trust the signals guiding our decisions.”

48%

Faster month-end close

32%

Increase in internal team satisfaction

Clara Nguyen

Head of Finance

“Manifold Health gave us immediate visibility into biological risk across systems. We identified multiple early deviations in the first week—and now every decision is grounded in real-time biological data.”

37%

Reduction in budget overages

2x

Faster spend approvals

Darius Finch

Finance Director

“Before Manifold Health, we were reacting to fragmented data and late signals. Now we have a unified view of biology, continuously updated insight, and early alerts—meaning fewer surprises and more time to focus on long-term health outcomes.”

3.4 h

Saved per team member each week

45%

Fewer manual reconciliation tasks

Meera Shah

Controller

“Manifold Health dramatically improved the clarity and reliability of our biological data. Our insights are cleaner, our team is less reactive, and we finally trust the signals guiding our decisions.”

48%

Faster month-end close

32%

Increase in internal team satisfaction

Clara Nguyen

Head of Finance

“Manifold Health gave us immediate visibility into biological risk across systems. We identified multiple early deviations in the first week—and now every decision is grounded in real-time biological data.”

37%

Reduction in budget overages

2x

Faster spend approvals

Darius Finch

Finance Director

“Before Manifold Health, we were reacting to fragmented data and late signals. Now we have a unified view of biology, continuously updated insight, and early alerts—meaning fewer surprises and more time to focus on long-term health outcomes.”

3.4 h

Saved per team member each week

45%

Fewer manual reconciliation tasks

Meera Shah

Controller

“Manifold Health dramatically improved the clarity and reliability of our biological data. Our insights are cleaner, our team is less reactive, and we finally trust the signals guiding our decisions.”

48%

Faster month-end close

32%

Increase in internal team satisfaction

Integrate once. Model everywhere.

Manifold Health connects directly to your existing data infrastructure—so biological signals, outcomes, and risk models stay consistent, current, and interoperable across systems.

Frequently asked questions

Answers to common questions about getting started and using Manifold Health day to day.

Book a demo call

Let’s talk about your current setup and see how Manifold Health can simplify your risk bearing operations.

Do you prefer email? We're available at:

Book a demo call

Let’s talk about your current setup and see how Manifold Health can simplify your risk bearing operations.

Do you prefer email? We're available at:

Book a demo call

Let’s talk about your current setup and see how Manifold Health can simplify your risk bearing operations.

Do you prefer email? We're available at:

Does Manifold Health replace primary care or clinicians?
icon

No. Manifold Health does not replace clinicians or deliver medical care. The platform provides biological insight and predictive health intelligence that complements existing care models by improving visibility into risk and trajectories earlier in the process.

How long does onboarding take?
icon

Most organizations are up and running in days, not months. Manifold Health provides guided onboarding, validated data pipelines, and clear implementation support to ensure rapid deployment without disrupting existing systems.

What data does Manifold Health use?
icon

Manifold Health is anchored in gold-standard blood-based biomarker data, and may also incorporate additional health, demographic, or longitudinal data where contractually agreed.

What is a Digital Health Twin?
icon

A Digital Health Twin is a continuously updated computational model of an individual’s or population’s biology. Manifold Health uses blood-based signals to model how biological systems interact over time—enabling early risk detection and forward-looking insight rather than static results.

Is Manifold Health compliant with data privacy and security standards?
icon

Yes. Manifold Health is designed with enterprise-grade security and processes data in accordance with applicable data protection laws. Access controls, encryption, and contractual safeguards are built into the platform.

Does Manifold Health replace primary care or clinicians?
icon

No. Manifold Health does not replace clinicians or deliver medical care. The platform provides biological insight and predictive health intelligence that complements existing care models by improving visibility into risk and trajectories earlier in the process.

How long does onboarding take?
icon

Most organizations are up and running in days, not months. Manifold Health provides guided onboarding, validated data pipelines, and clear implementation support to ensure rapid deployment without disrupting existing systems.

What data does Manifold Health use?
icon

Manifold Health is anchored in gold-standard blood-based biomarker data, and may also incorporate additional health, demographic, or longitudinal data where contractually agreed.

What is a Digital Health Twin?
icon

A Digital Health Twin is a continuously updated computational model of an individual’s or population’s biology. Manifold Health uses blood-based signals to model how biological systems interact over time—enabling early risk detection and forward-looking insight rather than static results.

Is Manifold Health compliant with data privacy and security standards?
icon

Yes. Manifold Health is designed with enterprise-grade security and processes data in accordance with applicable data protection laws. Access controls, encryption, and contractual safeguards are built into the platform.

Does Manifold Health replace primary care or clinicians?
icon

No. Manifold Health does not replace clinicians or deliver medical care. The platform provides biological insight and predictive health intelligence that complements existing care models by improving visibility into risk and trajectories earlier in the process.

How long does onboarding take?
icon

Most organizations are up and running in days, not months. Manifold Health provides guided onboarding, validated data pipelines, and clear implementation support to ensure rapid deployment without disrupting existing systems.

What data does Manifold Health use?
icon

Manifold Health is anchored in gold-standard blood-based biomarker data, and may also incorporate additional health, demographic, or longitudinal data where contractually agreed.

What is a Digital Health Twin?
icon

A Digital Health Twin is a continuously updated computational model of an individual’s or population’s biology. Manifold Health uses blood-based signals to model how biological systems interact over time—enabling early risk detection and forward-looking insight rather than static results.

Is Manifold Health compliant with data privacy and security standards?
icon

Yes. Manifold Health is designed with enterprise-grade security and processes data in accordance with applicable data protection laws. Access controls, encryption, and contractual safeguards are built into the platform.

New York, NY, USA

@ 2025 Manifold Health All rights reserved

Manifold Health is a health intelligence software provider, not a healthcare provider, insurer, health plan, or medical device manufacturer. The services provided by Manifold Health are intended solely for business and enterprise use and do not include the provision of medical care, diagnosis, treatment, insurance coverage, or payment processing. Manifold Health’s platform is designed to enhance visibility, automation, and decision-making across population health, risk modeling, and cost management workflows. Insights generated by the platform are intended for informational and operational planning purposes only and should not be interpreted as medical advice, clinical guidance, underwriting determinations, or a substitute for professional medical, actuarial, legal, or financial consultation. Access to the Manifold Health platform is subject to our Terms of Use and Privacy Policy. Data entered into the platform is processed in accordance with applicable data protection and privacy laws and stored using enterprise-grade security controls. Manifold Health makes no representations or guarantees regarding clinical outcomes, cost savings, compliance determinations, underwriting decisions, or financial performance resulting from use of the platform. All third-party data sources, integrations, and APIs are provided “as is,” and Manifold Health assumes no responsibility for the accuracy, availability, or continued support of connected services. Manifold Health does not perform claims adjudication, insurance underwriting, regulatory reporting, or clinical decision-making unless explicitly agreed upon through a written service agreement. Use of the Manifold Health platform may involve the transmission of health, claims, eligibility, or laboratory data through secure APIs or manually uploaded files. Customers are solely responsible for ensuring the accuracy of their data, maintaining compliance with applicable laws and regulations (including HIPAA where applicable), and determining how platform insights are used within their organization. Any predictive models, forecasts, or AI-driven insights provided by Manifold Health are forward-looking in nature and should not be relied upon as the sole basis for healthcare, coverage, or financial decisions. Manifold Health is not intended for personal or consumer use. Availability of features—including analytics, forecasting, and automation—may vary by plan level, data source, and geographic region. Manifold Health, Inc. is a privately held company registered in the United States of America. For questions regarding platform usage, licensing, data security, or compliance, please refer to our Help Center or contact support@manifoldhealth.ai.

New York, NY, USA

@ 2025 Manifold Health All rights reserved

Manifold Health is a health intelligence software provider, not a healthcare provider, insurer, health plan, or medical device manufacturer. The services provided by Manifold Health are intended solely for business and enterprise use and do not include the provision of medical care, diagnosis, treatment, insurance coverage, or payment processing. Manifold Health’s platform is designed to enhance visibility, automation, and decision-making across population health, risk modeling, and cost management workflows. Insights generated by the platform are intended for informational and operational planning purposes only and should not be interpreted as medical advice, clinical guidance, underwriting determinations, or a substitute for professional medical, actuarial, legal, or financial consultation. Access to the Manifold Health platform is subject to our Terms of Use and Privacy Policy. Data entered into the platform is processed in accordance with applicable data protection and privacy laws and stored using enterprise-grade security controls. Manifold Health makes no representations or guarantees regarding clinical outcomes, cost savings, compliance determinations, underwriting decisions, or financial performance resulting from use of the platform. All third-party data sources, integrations, and APIs are provided “as is,” and Manifold Health assumes no responsibility for the accuracy, availability, or continued support of connected services. Manifold Health does not perform claims adjudication, insurance underwriting, regulatory reporting, or clinical decision-making unless explicitly agreed upon through a written service agreement. Use of the Manifold Health platform may involve the transmission of health, claims, eligibility, or laboratory data through secure APIs or manually uploaded files. Customers are solely responsible for ensuring the accuracy of their data, maintaining compliance with applicable laws and regulations (including HIPAA where applicable), and determining how platform insights are used within their organization. Any predictive models, forecasts, or AI-driven insights provided by Manifold Health are forward-looking in nature and should not be relied upon as the sole basis for healthcare, coverage, or financial decisions. Manifold Health is not intended for personal or consumer use. Availability of features—including analytics, forecasting, and automation—may vary by plan level, data source, and geographic region. Manifold Health, Inc. is a privately held company registered in the United States of America. For questions regarding platform usage, licensing, data security, or compliance, please refer to our Help Center or contact support@manifoldhealth.ai.

New York, NY, USA

@ 2025 Manifold Health All rights reserved

Manifold Health is a health intelligence software provider, not a healthcare provider, insurer, health plan, or medical device manufacturer. The services provided by Manifold Health are intended solely for business and enterprise use and do not include the provision of medical care, diagnosis, treatment, insurance coverage, or payment processing. Manifold Health’s platform is designed to enhance visibility, automation, and decision-making across population health, risk modeling, and cost management workflows. Insights generated by the platform are intended for informational and operational planning purposes only and should not be interpreted as medical advice, clinical guidance, underwriting determinations, or a substitute for professional medical, actuarial, legal, or financial consultation. Access to the Manifold Health platform is subject to our Terms of Use and Privacy Policy. Data entered into the platform is processed in accordance with applicable data protection and privacy laws and stored using enterprise-grade security controls. Manifold Health makes no representations or guarantees regarding clinical outcomes, cost savings, compliance determinations, underwriting decisions, or financial performance resulting from use of the platform. All third-party data sources, integrations, and APIs are provided “as is,” and Manifold Health assumes no responsibility for the accuracy, availability, or continued support of connected services. Manifold Health does not perform claims adjudication, insurance underwriting, regulatory reporting, or clinical decision-making unless explicitly agreed upon through a written service agreement. Use of the Manifold Health platform may involve the transmission of health, claims, eligibility, or laboratory data through secure APIs or manually uploaded files. Customers are solely responsible for ensuring the accuracy of their data, maintaining compliance with applicable laws and regulations (including HIPAA where applicable), and determining how platform insights are used within their organization. Any predictive models, forecasts, or AI-driven insights provided by Manifold Health are forward-looking in nature and should not be relied upon as the sole basis for healthcare, coverage, or financial decisions. Manifold Health is not intended for personal or consumer use. Availability of features—including analytics, forecasting, and automation—may vary by plan level, data source, and geographic region. Manifold Health, Inc. is a privately held company registered in the United States of America. For questions regarding platform usage, licensing, data security, or compliance, please refer to our Help Center or contact support@manifoldhealth.ai.