


health systems
Take control of chronic conditions.
True employee engagement, clinical outcomes, and cost control across the entire chronic care journey is the reality, with Manifold.
Flexible Programs and Pricing

Conquer the complexities of
chronic care
For health systems participating in value-based care and accountable care models, chronic conditions remain one of the largest drivers of utilization, readmissions, and total cost of care. To improve outcomes and financial performance, organizations must look beyond episodic clinical encounters and address avoidable issues such as low screening rates, poor follow-up, delayed risk identification, care gaps, and limited visibility into patient health between visits. These are the factors that ultimately drive utilization, quality metrics, and long-term costs.
Most traditional approaches are reactive, relying on claims data and interventions that arrive too late to meaningfully change outcomes. With Manifold, health systems gain continuous visibility into population health through self-collected blood testing, longitudinal monitoring, and proactive care management—helping improve quality performance, reduce avoidable utilization, and succeed under value-based care arrangements.
The Manifold Health shift, straight from our clients

Clara Nguyen
Head of Clinical Care
"Manifold changed how we manage patients between visits. The at-home collection means people actually follow through, no lab trips, no missed draws, so we finally have continuous biological data instead of reading symptoms and guessing. We can see exactly how each patient is responding over time and step in early."
52%
Increased Bloodwork Completion
3.2x
Therapy Adherence

Darius Finch
Finance Director
“Before Manifold Health, we were reacting to symptoms, fragmented data, and late-stage diagnoses. Now we have a unified view of biology, early risk signals, and predictive insight — which means fewer surprises and more time to focus on prevention and long-term health outcomes.”
3.4 h
Saved per team member each week
45%
Fewer manual reconciliation tasks

Meera Shah
Controller
“Manifold Health helped us move from reactive care to earlier insight. Our biological data is cleaner, our models are more reliable, and we finally trust the signals we’re seeing.”
48%
Faster month-end close
32%
Increase in internal team satisfaction

Clara Nguyen
Head of Clinical Care
"Manifold changed how we manage patients between visits. The at-home collection means people actually follow through, no lab trips, no missed draws, so we finally have continuous biological data instead of reading symptoms and guessing. We can see exactly how each patient is responding over time and step in early."
52%
Increased Bloodwork Completion
3.2x
Therapy Adherence

Darius Finch
Finance Director
“Before Manifold Health, we were reacting to symptoms, fragmented data, and late-stage diagnoses. Now we have a unified view of biology, early risk signals, and predictive insight — which means fewer surprises and more time to focus on prevention and long-term health outcomes.”
3.4 h
Saved per team member each week
45%
Fewer manual reconciliation tasks

Meera Shah
Controller
“Manifold Health helped us move from reactive care to earlier insight. Our biological data is cleaner, our models are more reliable, and we finally trust the signals we’re seeing.”
48%
Faster month-end close
32%
Increase in internal team satisfaction

Clara Nguyen
Head of Clinical Care
"Manifold changed how we manage patients between visits. The at-home collection means people actually follow through, no lab trips, no missed draws, so we finally have continuous biological data instead of reading symptoms and guessing. We can see exactly how each patient is responding over time and step in early."
52%
Increased Bloodwork Completion
3.2x
Therapy Adherence

Darius Finch
Finance Director
“Before Manifold Health, we were reacting to symptoms, fragmented data, and late-stage diagnoses. Now we have a unified view of biology, early risk signals, and predictive insight — which means fewer surprises and more time to focus on prevention and long-term health outcomes.”
3.4 h
Saved per team member each week
45%
Fewer manual reconciliation tasks

Meera Shah
Controller
“Manifold Health helped us move from reactive care to earlier insight. Our biological data is cleaner, our models are more reliable, and we finally trust the signals we’re seeing.”
48%
Faster month-end close
32%
Increase in internal team satisfaction


What Manifold delivers

What Manifold delivers
74% of lifestyle-related deaths are caused by chronic conditions.
74% of lifestyle-related deaths are caused by chronic conditions.
74% of lifestyle-related deaths are caused by chronic conditions.
>53% reduction in prescription use among ages 45-79.
>53% reduction in prescription use among ages 45-79.
>53% reduction in prescription use among ages 45-79.
Chronic conditions can cost up to seven times more than if they had been prevented.
Chronic conditions can cost up to seven times more than if they had been prevented.
Chronic conditions can cost up to seven times more than if they had been prevented.
saved per patient
saved per patient
saved per patient
GLP-1 Removal
GLP-1 Removal
GLP-1 Removal
Return on Investment in Year 1
Return on Investment in Year 1
Return on Investment in Year 1
PREVENTATIVE HEALTH
Detect conditions earlier, prevent expensive health costs.
Every lifestyle-related chronic condition managed earlier saves tens of thousands in treatment costs and delivers 2–3x better health outcomes on average.

Continuous biological monitoring
Track key biological systems over time as new blood data is collected. Manifold Health updates the Digital Health Twin continuously—revealing subtle changes long before clinical symptoms emerge.
Continuous biological monitoring
Track key biological systems over time as new blood data is collected. Manifold Health updates the Digital Health Twin continuously—revealing subtle changes long before clinical symptoms emerge.
Continuous biological monitoring
Track key biological systems over time as new blood data is collected. Manifold Health updates the Digital Health Twin continuously—revealing subtle changes long before clinical symptoms emerge.
System-level thresholds limits & rules
Define biologically meaningful ranges across metabolic, inflammatory, cardiovascular, and hormonal systems. Our models evaluate how signals interact—rather than relying on isolated biomarkers.
System-level thresholds limits & rules
Define biologically meaningful ranges across metabolic, inflammatory, cardiovascular, and hormonal systems. Our models evaluate how signals interact—rather than relying on isolated biomarkers.
System-level thresholds limits & rules
Define biologically meaningful ranges across metabolic, inflammatory, cardiovascular, and hormonal systems. Our models evaluate how signals interact—rather than relying on isolated biomarkers.
Early deviation detection
Identify when biology begins to drift from healthy trajectories. Manifold Health flags compounding risk patterns early—when intervention is still effective and outcomes are more favorable.
Early deviation detection
Identify when biology begins to drift from healthy trajectories. Manifold Health flags compounding risk patterns early—when intervention is still effective and outcomes are more favorable.
Early deviation detection
Identify when biology begins to drift from healthy trajectories. Manifold Health flags compounding risk patterns early—when intervention is still effective and outcomes are more favorable.

Key Insights
Focused on the key conditions responsible for most preventable diseases.

Key Insights
Focused on the key conditions responsible for most preventable diseases.

Key Insights
Focused on the key conditions responsible for most preventable diseases.
Frequently asked questions
Manifold helps health systems identify risk earlier, engage patients more effectively, and monitor health continuously between clinical encounters. Through self-collected blood testing and longitudinal health intelligence, organizations gain greater visibility into patient populations, helping improve quality performance and reduce avoidable utilization.
Manifold addresses many of the drivers of avoidable healthcare spending, including delayed risk identification, poor follow-up, low patient engagement, unmanaged chronic conditions, and care gaps. By enabling earlier intervention and continuous monitoring, organizations can reduce downstream utilization and improve population health outcomes.
Manifold extends population health programs beyond the clinic by bringing screening, monitoring, and patient engagement directly into the home. This helps organizations reach more patients, improve participation rates, and maintain visibility into health status over time.
Manifold uses biomarker monitoring, proactive outreach, and longitudinal health tracking to identify patients who may be missing screenings, follow-up care, or chronic disease management opportunities. This helps care teams prioritize interventions and improve quality performance.
No. Manifold is designed to complement existing care management, disease management, and population health initiatives. We provide a continuous biological monitoring layer that helps organizations understand patient risk, engagement, and outcomes between traditional care encounters.
Manifold combines guided self-collected blood testing, digital engagement, and proactive monitoring to meet patients where they are. By reducing barriers to participation and making health information more accessible, organizations can improve adherence and long-term engagement.
y improving screening completion, patient engagement, chronic disease monitoring, and care gap closure, Manifold helps organizations improve performance across quality measures and value-based reimbursement programs while creating greater visibility into population health risk.
Manifold helps health systems identify risk earlier, engage patients more effectively, and monitor health continuously between clinical encounters. Through self-collected blood testing and longitudinal health intelligence, organizations gain greater visibility into patient populations, helping improve quality performance and reduce avoidable utilization.
Manifold addresses many of the drivers of avoidable healthcare spending, including delayed risk identification, poor follow-up, low patient engagement, unmanaged chronic conditions, and care gaps. By enabling earlier intervention and continuous monitoring, organizations can reduce downstream utilization and improve population health outcomes.
Manifold extends population health programs beyond the clinic by bringing screening, monitoring, and patient engagement directly into the home. This helps organizations reach more patients, improve participation rates, and maintain visibility into health status over time.
Manifold uses biomarker monitoring, proactive outreach, and longitudinal health tracking to identify patients who may be missing screenings, follow-up care, or chronic disease management opportunities. This helps care teams prioritize interventions and improve quality performance.
No. Manifold is designed to complement existing care management, disease management, and population health initiatives. We provide a continuous biological monitoring layer that helps organizations understand patient risk, engagement, and outcomes between traditional care encounters.
Manifold combines guided self-collected blood testing, digital engagement, and proactive monitoring to meet patients where they are. By reducing barriers to participation and making health information more accessible, organizations can improve adherence and long-term engagement.
y improving screening completion, patient engagement, chronic disease monitoring, and care gap closure, Manifold helps organizations improve performance across quality measures and value-based reimbursement programs while creating greater visibility into population health risk.
Manifold helps health systems identify risk earlier, engage patients more effectively, and monitor health continuously between clinical encounters. Through self-collected blood testing and longitudinal health intelligence, organizations gain greater visibility into patient populations, helping improve quality performance and reduce avoidable utilization.
Manifold addresses many of the drivers of avoidable healthcare spending, including delayed risk identification, poor follow-up, low patient engagement, unmanaged chronic conditions, and care gaps. By enabling earlier intervention and continuous monitoring, organizations can reduce downstream utilization and improve population health outcomes.
Manifold extends population health programs beyond the clinic by bringing screening, monitoring, and patient engagement directly into the home. This helps organizations reach more patients, improve participation rates, and maintain visibility into health status over time.
Manifold uses biomarker monitoring, proactive outreach, and longitudinal health tracking to identify patients who may be missing screenings, follow-up care, or chronic disease management opportunities. This helps care teams prioritize interventions and improve quality performance.
No. Manifold is designed to complement existing care management, disease management, and population health initiatives. We provide a continuous biological monitoring layer that helps organizations understand patient risk, engagement, and outcomes between traditional care encounters.
Manifold combines guided self-collected blood testing, digital engagement, and proactive monitoring to meet patients where they are. By reducing barriers to participation and making health information more accessible, organizations can improve adherence and long-term engagement.
y improving screening completion, patient engagement, chronic disease monitoring, and care gap closure, Manifold helps organizations improve performance across quality measures and value-based reimbursement programs while creating greater visibility into population health risk.











